Chelation Therapy

What is Chelation Therapy?
Chelation is defined as the incorporation of a metal ion into a heterocyclic ring structure. In simple terms chelation therapy is well documented and used widely around the world for removal of toxic metals from the human body. Lead toxicity, mercury intoxication, Iron overload and cadmium deposition in the body is well known to produce disease. Chelation therapy is usually the treatment of choice for these problems. An off-label use of EDTA chelation therapy has been utilized since the 1950′s as an adjunctive treatment for vascular disease including coronary, peripheral and carotid.  Dr. Anello recommends that everyone follow the recommendations of their cardiologist along with the implementation of Chelation, if it is warranted.

Clinical experience has demonstrated that chelation has been used successfully in millions of patients with heavy metal toxicity, coronary artery disease and peripheral vascular disease. .

For more information about Chelation Therapy and how it works please go to the article on Chelation Therapy.

chelation1-300x239Initial Visit
On your first visit the physician will review your medical history with you. You are requested to complete a Patient Questionnaire beforehand which will assist in this initial evaluation. (This questionnaire can be obtained at the office or you can put in a request by phone.) A complete physical examination concentrating upon your particular situation will also be carried out at the initial visit. If you decide to proceed with chelation treatments a laboratory requisition will be given for a number of hematological and biochemical tests. General kidney function tests, vitamin and mineral levels as well as novel risk factors for cardiovascular disease will be assessed.

Vitamins and Supplements
After your first treatment Dr. Anello or staff will review your laboratory results with you. Any deficiencies in vitamins, minerals or hormones will be discussed and a replacement program prescribed. EDTA chelation therapy is a nutrient-requiring-process and vitamins and mineral supplements will be required during your treatment. Other nutrients or nutriceuticals will be discussed dependant upon your individual needs. Many of the supplements are available through the Clinic as they are deemed part of the chelation treatment. “These supplements are provided at cost to our patients.”

Where, When and How.
Chelation treatments are scheduled at the Anello Clinic at 401 Laurel Street in Cambridge Ontario. (A map of how to get to the Anello Clinic is on the location page.) Chelation is an intravenous treatment. The treatment typically takes 2 to 21/2 hours. Our nurses will start your intravenous after taking your blood pressure. You are asked to drink plenty of water both before, during and after the treatment (1.5 – 2 litres of water in an 10 – 12 hour period). Please refrain from caffeine beverages, heavy exercise and calcium supplements on the day of chelation.

Number of Treatments
The number of chelation treatments varies according to individual factors such as severity of disease, chronicity, kidney function and overall health. On average 20 to 30 treatments are required for therapeutic value. Benefits may not be noticeable for three months after treatments. “Maintenance treatments, ranging from monthly to a few times a year, may be recommended to maintain the benefit.”

Contents of Chelation Treatments
The following is contained in most chelation intravenous treatments. Each intravenous is custom formulated according to the patients kidney function, disease and vitamin/mineral status. “The following ingredients are mixed in a carrier solution of sterile water, dextrose water or Ringers Lactate iv solution.”

EDTA this is the chelating agent. From 1 gram to 3 grams is utilized

ASCORBIC ACID (VITAMIN C) this major antioxidant also has chelating qualities. It protects against free radical damage, improves collagen cross linking, helps cell integrity and boosts the immune system.

Magnesium is often frankly deficient or low in most people. Magnesium is important in lowering blood pressure, has a role in preventing arrhythmias, aids in muscle relaxation and is required in some 300 different enzymatic reaction in the body.

SODIUM BICARBONATE Alkalinizing agent, buffers the solution.

B VITAMINS Thiamine, riboflavin, niacinamide, pantothenic acid, pyridoxine, methylcobalamin. The B vitamins aid in preventing arteriosclerosis, helps in immune functioning, essential in brain and nervous system functioning and aids in energy production.

GLUTATHIONE this important nutrient helps make energy production more efficient and is a powerful antioxidant, protector of the mitochondrion organelles in the cells. Glutathione is added on an intermittent basis in order to maintain levels in brain and nervous system.


Trial to Assess Chelation Therapy  (TACT): Results

Simply put the TACT trial showed chelation was a safe addition to standard medical/interventional cardiology care and that those receiving chelation had an 18% reduced risk of subsequent cardiac events such as heart attack, stroke, hospitalization for angina, or coronary re-vascularization.  Diabetics fared even better showing a 43% reduction in death from all causes.

The TACT trial showed such surprisingly good results that a second trial TACT-2 is presently underway with diabetics only.  If the results are replicated chelation may become the standard of care to reduce cardiac complications in diabetes.